Dr John Elliotson is the Templar physician behind Starrick's Soothing Syrup, the addictive tonic dulling London's poor. Jacob Frye tracks him down through Sequence 4 with Charles Darwin's help, and he is the target of the memory Overdose at Lambeth Asylum.
Jacob destroys the Syrup distillery with Darwin, who points him to shipments going to Lambeth Asylum. Jacob then scares the asylum's owner Richard Owen into naming Elliotson. Overdose's optional objectives include halting an electroconvulsive therapy session and not firing a single bullet.
Elliotson accidentally kills a patient during a trepanation demonstration and sends for a fresh corpse. Jacob takes the body's place, is wheeled into the auditorium and kills him, ending the Syrup for good.
The asylum closes and fake tonics flood the city. Evie helps Florence Nightingale make medicine in The Lady with the Lamp, and Cardigan and Twopenny bring their worries to Starrick.
After his death a mourning woman appears in cemeteries and at St Paul's, Covent Garden, blaming the Blighters for getting John killed. The game's period-style murder ballad Give Me the Cure is about his end, though it calls him only the doctor.
OverdoseOverdose is the assassination of Dr John Elliotson inside Lambeth Asylum. As Jacob you explore the asylum, help a trapped nurse and stop a brutal electroshock session, then reach Elliotson's lecture theatre by hiding under the sheet of a cadaver.Crawford Starrick
Crawford Starrick is the main antagonist of Assassin's Creed Syndicate: Grand Master of the British Templars and the industrialist who controls London in 1868 through his factories, railways, banks, the Blighters gang and a ring of Templar lieutenants. Every major target the Frye twins kill is one of his people, and the main story builds toward a final confrontation with him at Buckingham Palace.
Charles Darwin
Charles Darwin helps Jacob destroy the Soothing Syrup distillery in Sequence 4 and then gives the Charles Darwin London Stories, in which the twins protect his work and reputation from Templar-backed attacks.
Richard Owen
Richard Owen is the naturalist and Darwin rival Jacob chases down in On the Origin of Syrup. Rammed through traffic in his own carriage, he gives up the name of the Syrup's creator: Dr John Elliotson of Lambeth Asylum.
Florence Nightingale
Florence Nightingale is stationed at Lambeth Asylum in 1868. In The Lady with the Lamp she treats Clara O'Dea and asks Evie to recover the supplies needed to replace the counterfeit tonics flooding Lambeth after John Elliotson's death.