College Wharf is a Southwark loading dock on the Thames. You go there for Alexander Graham Bell in Cable News, freeing his crew and recovering seized cable reels, and later return to help set an ambush on Templar dynamite smugglers.
The Blighters have taken Bell's crew hostage and seized his cable. The twins free the crew and recover all three reels, then have to escape when a Blighter cargo boat spots them.
Later, one twin returns to help Alfred Fleming, head of the Queen's Secret Service, plan an ambush on Templars smuggling dynamite in through the docks.
Bell has just fitted the twins' gauntlets with hallucinogenic darts, and he has learned that the serum turns into a gas when heated. That is why the full-sync goal asks you to shoot fire sources near groups of Blighters at the wharf: the burning dart releases the gas among them. While recovering the reels the twins also find that the Blighters are shipping poison for Starrick, which they report back to Bell.
Jacob's Island
Jacob's Island is one of Octavia Plumb's two Blighter strongholds in Southwark, a disease-ridden riverside slum. Clearing it turns it into a Rook stronghold.
London Bridge station
London Bridge station is the oldest railway terminus in London, opened in 1836, at the southern end of London Bridge in Southwark.
Starrick Warehouse
The Starrick Warehouse is an abandoned Southwark warehouse used to hide stolen Punjabi gold in The Last Maharaja. In A Golden Path you help Duleep Singh hijack the gold carriage.
The Mint
The Mint is one of Octavia Plumb's two Blighter strongholds in Southwark. Taking it hands the site to the Rooks.