Chosen One is a gear perk that improves your general defense after a takedown. It makes you tougher right after a silent kill when nearby guards may react.
After every takedown you take less damage for a while. If a takedown gets spotted, you are better protected in the fight that follows.
Wear one of the gear pieces that carry it: Prophet's Bands. Each piece only takes one body slot, so plan around the other perks you want.
Good for players who mix stealth and combat. Pure gunfighters will rarely trigger it.
Pairs well with Bullet Ballet, which refills your mag after a takedown.