Clara O'Dea is the young girl who runs London's network of street urchins and pickpockets. She trades her intelligence to Jacob and Evie Frye on one condition: that they free the children forced to work in the city's factories, which is the Child Liberation activity.
In To Catch an Urchin the twins have to chase Clara down, and she relieves Jacob of most of his money along the way. She agrees to share what her urchins see and hear in return for freed child workers, and she and Evie seal the deal by spitting in their hands and shaking.
Clara's mother was an Irish servant in a wealthy Strand household, and Clara picked up an education by listening in on the family's private lessons. After her mother was wrongly accused of theft and dismissed, and her father left, Clara was supporting the household by the age of ten. When her mother died she turned to looking after other children.
After Jacob kills John Elliotson, counterfeit tonics flood Lambeth and Clara's children fall ill. Clara herself collapses at Lambeth Asylum into Evie's arms, and Florence Nightingale treats her while Evie recovers the supplies for a cure. Once every child labour factory is shut down, Clara thanks the twins and hugs Evie.
Florence Nightingale
Florence Nightingale is stationed at Lambeth Asylum in 1868. In The Lady with the Lamp she treats Clara O'Dea and asks Evie to recover the supplies needed to replace the counterfeit tonics flooding Lambeth after John Elliotson's death.
John Elliotson
Dr John Elliotson is the Templar physician behind Starrick's Soothing Syrup, the addictive tonic dulling London's poor. Jacob Frye tracks him down through Sequence 4 with Charles Darwin's help, and he is the target of the memory Overdose at Lambeth Asylum.
Charles Dickens
Charles Dickens gives the Ghost Club London Stories in Syndicate. He signs the Frye twins up to investigate London's hauntings and monsters, from Spring-heeled Jack to the most haunted house in the city, and nearly every case turns out to have a human culprit.
Evie Frye
Evie Frye is the second playable Assassin in Assassin's Creed Syndicate and the planner of the Frye twins. While Jacob tears down Starrick's businesses, her memories follow the hunt for a Shroud of Eden across London and her rivalry with the Templar occultist Lucy Thorne. She is also the playable lead of the 1888 Jack the Ripper story.